Scientist Profiles

Ingrid Oakley-Girvan, Ph.D., M.P.H. Research Scientist, Northern California Cancer Center Consulting Assistant Professor, Dept. of Health Research and Policy, Stanford University School of Medicine Member, Stanford Cancer Center

2201 Walnut Avenue, Suite 300
Fremont, California 94538-2334
E-mail: ioakley@nccc.org
Phone: 510-608-5045
Fax: 510-608-5085

Research Interests:

• Evaluating factors associated with racial disparities in prostate cancer diagnosis, progression and survival
• Evaluating genetic factors and gene/environment interactions involved in prostate cancer incidence, progression and survival
• Evaluating genetic factors and gene/environment interactions involved in ovarian cancer incidence and survival
• Assessing quality of life and survivorship issues two or more years after diagnosis

Dr. Oakley-Girvan's research concentrates on studies of breast, ovarian and prostate cancer with an emphasis on genetic epidemiology and survivorship.

Genetic epidemiology: Identifying genes that increase susceptibility to cancer or are related to poor survival is a primary interest of Dr. Oakley-Girvan. She is part of the International Consortium for Prostate Cancer Genetics and a member in an international breast and ovarian cancer research group. Through these collaborative teams, which include a broad base of investigators from many institutions and genetic samples from many projects, Dr. Oakley-Girvan is able to focus on investigating genes that may increase a person's susceptibility to prostate, ovarian and breast cancer. In addition, she aims to identify environmental factors that reduce an individual's risk of these cancers, as well as decrease their risk of cancer recurrence and improve their chance of survival.

Survivorship: Dr. Oakley-Girvan is also actively evaluating factors associated with cancer treatment choice, quality of care, treatment outcomes and quality of life. With interests throughout the cancer survivorship continuum and an emphasis on understanding why there are disparities in survivor care, Dr. Oakley-Girvan is also focused on creating solutions. She plans to follow her current studies with education and intervention projects that will effect meaningful change, improve the life of survivors and help eliminate, or, at the very least, reduce cancer health care disparities.

Selected Research Projects:

Haiman CA, Patterson N, Freedman ML, Myers SR, Pike MC, Waliszewska A, Neubauer J, Tandon A, Schirmer C, McDonald GJ, Greenway SC, Stram DO, Marchand LL, Kolonel LN, Frasco M, Wong D, Pooler LC, Ardlie K, Oakley-Girvan I, Whittemore AS, Cooney KA, John EM, Ingles SA, Altshuler D, Henderson BE and Reich D: Multiple regions within 8q24 independently affect risk for prostate cancer.  Nat Genet 2007; 39(5):638-44.

Bloom JR, Stewart SL, Oakley-Girvans I, Banks PJ, Chang S.  Family history, perceived risk and prostate cancer screening among African-American men.  CEBP 2006; 15(11):2167-73. 

Freedman ML, Haiman CA, Patterson N, McDonald GJ, Tandon A, Waliszewska A, Penney K, Montague C, Ardlie K, John EM, Oakley-Girvan I, Whittemore AS, Cooney KA, Ingles SA, Altshuler D, Henderson BE, Reich D.  Admixture mapping identifies 8q24 as an early onset prostate cancer locus in African American men. Proc Natl Acad Sci USA 2006; 103(38):14068-14073. 

Xu J, Dimitrov L, Chang BL, Meyers DA, Eeles R, Easton D, Foulkes W, Simard J, Badzioch M, Hopper J, Giles G, Mahle L, Moller P, Bishop T, Evans C, Edwards  S, Meitz J, Bullock S, Hope Q, Hsieh CL, Halpern J, Balise  RR, Oakley-Girvan I, Whittemore AS, Wiley KE, Isaacs SD, Ewing CM, Gielzak M, Walsh PC, Isaacs WB, Thibodeau SN, McDonnell SK, Cunningham JM, Zarfas KE, Hebbring S, Schaid DJ, Friedrichsen DM, Deutsch K, Kolb S, Jarvik GP, Janer M, Hood L, Ostrander EA, Stanford  J, Lange EM, Beebe-Dimmer JL, Mohai C, Cooney KA, Ikonen T, Baffoe-Bonnie A, Fredriksson H, Matikainen MP, Tammela TLJ, Bailey-Wilson J, Schleutker  J, Maier C, Herkommer K, Hoegel  J, Vogel W, Paiss T, Wiklund F, Emanuelsson M, Stenman E, Jonsson BA, Grönberg H, Seminara D:  A combined genomewide linkage scan of 1,233 families for prostate cancer-susceptibility genes conducted by the international consortium for prostate cancer genetics. Am J of Hum Genet 2005; 77(2): 219-229.

Schaid DJ, Chang BL, and The International Consortium for Prostate Cancer Genetics (BC/CA/HI/SF Group:  Balise RR, Gallagher RP, Halpern J, Hsieh C, Kolonel LN, Oakley-Girvan I, West DW, Whittemore AS and Wu A):  Description of the International Consortium for Prostate Cancer Genetics, and failure to replicate linkage of hereditary prostate cancer to 20q13. The Prostate 2005; 63: 276-290. 

All publications (22)


Education:

Web site Links:
Stanford website for Dr. Oakley-Girvan:
http://med.stanford.edu/profiles/Ingrid_Oakley-Girvan/

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