This review summarizes recent literature addressing the epidemiologic characteristics of HIV-associated lymphomas with particular attention to the impact of highly active antiretroviral therapy (HAART). The introduction of HAART in 1996 dramatically changed the natural history of HIV infection, and the epidemiology of HIV-associated lymphomas now differs from that observed in the first 15 years of the HIV epidemic. Substantial reductions in non-Hodgkin lymphoma (NHL) incidence have been reported in populations with access to HAART immediately after its introduction, but long-term risks of NHL remain unknown.
NCCC Principal Investigator: Christina Clarke, Ph.D.
Funding Source: Surveillance, Epidemiology, and End Results (SEER) Program