Epidemiology of EBV-defined Hodgkin lymphoma
Epstein-Barr virus (EBV) is a very common virus that has been linked to some cases of Hodgkin lymphoma. However, little is known about why this virus appears to be involved with the tumor in some patients but not others. This registry-based study explores the relationship of EBV in Hodgkin lymphoma tumors to other patient characteristics, such as age, sex, and race, that are known to affect occurrence of this lymphoma. The study involves testing for the presence of EBV in stored samples from a large number of Hodgkin lymphoma tumors from persons diagnosed in California in 1992-97, and relating the findings to patient information previously collected by the Greater Bay Area Cancer Registry.
NCCC Principal Investigator: Sally L. Glaser, Ph.D.
Collaborators: Richard F. Ambinder, M.D., Ph.D., Johns Hopkins Medical School; Wendy Cozen, D.O., University of Southern California; Hoda Anton-Culver, Ph.D., University of California Irvine
Funding Source: National Cancer Institute
Publication: Glaser SL, Clarke CA, Gulley ML, Craig FE, DiGiuseppe JA, Dorfman RF, Mann RB, Ambinder RF. Population-based patterns of human immunodeficiency virus-related Hodgkin lymphoma in the Greater San Francisco Bay Area, 1988-98. Cancer 2003; 98:300-309. |
